Introduction of Medicinal chemistry

Medicinal chemistry introduction

Medicinal chemistry is the chemistry discipline concerned With the design development and conflation of pharmaceutical medicines.

It’s the combination of chemistry and pharmacology To identify, develop, and synthesise the pharmaceutical agents That have a remedial use and estimate the parcels of being medicines.

History of Medicinal chemistry

The early explorers set up that the south american Indians also masticated coca leaves( Containing Cocaine) and used mushrooms( Containing methylated tryptamine) as hallucinogens.

In anicient Greek apothecary shops sauces similar as opium, squill and hyocyamus, serpent poison and cadmium oxide could be set up.

Importance of Medicinal chemistry

The subject provides drugstore graduates with all through knowledge of medicine, medium of action, structure exertion relationship( SAR) Acid base and physio chemical parcels and ADMET immersion distribution, metabolism, excretion and toxin profile.

Use of Medicinal chemistry

The Medicinal druggist exploration and develop chemical composites that can be used.

Objectives of Medicinal chemistry

The main ideal of this subject is to design and product of composites that can be used in drug for the purpose of forestalment, treatment and cure of mortal or beast conditions.

Why we study Medicinal chemistry

This is because the medicinal druggists do exploration and develop chemical composites that can be used on pharmaceutical medicines.

The medicinal druggist work on brigades with other scientists and masterminds to creates or design and test new medicine products.

They also help develop new and advanced manufacturing processes to effectively produce new medicines on a large scale.

Design of medicinal chemistry

Medicine designs frequently appertained to as rational medicine design or simply rational design is the inventive process of chancing new specifics grounded on the knowledge of a natural target.

Importance of organic chemistry in medicinal chemistry

The organic chemistry is really veritably important for drug discovery.

Numerous drugs comes from natural sources through birth and that will profit for mortal health.

Likewise drugs from organic composites tend to be safer as compared to medicinal set from laboratory trials.

Importance of pharmacology in medicinal chemistry

Medicinal chemistry play a vital part in driving the medicine discovery design by counting on their knowledge and moxie in organic chemistry, biology of the complaint, in Vitro & in vivo Pharmacological webbing and Pharmacokinetic characteristics by maximizing the efficacy and minimizing the side goods.

Stages of medicinal chemistry

There are three stages that covers the medicinal chemistry.

Step 1 of medicinal chemistry

Discovery Step:

Involving Choice of remedial target( Receptor, Enzyme and target group, cellular in vivo model and identification or discovery and product of new active substances interacting with named targets similar emulsion called supereminent emulsion.

Step 2 of Medicinal chemistry

Step-II An optimization step:

Which deals with enhancement of supereminent emulsion

The Optimization process takes primarily into account the increase in energy selectivity and toxin.

Step 3 of Medicinal chemistry

Development  Stage -III:

Whose purpose is durability of enhancement of pharmacokinetic parcels.

Structure activity Relationship (SAR)

Presented by Crum brown and Frasin in 1865.

Structure determines the functions.

The structure of a emulsion/ or medicine determines natural effect it has so this determination of structure/ function connections helps medical druggists to conflation new medicines.

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What is the introduction of medicinal chemistry?

Medicinal chemistry introduction

How we introduced medicinal chemistry?

What is medicinal chemistry?

Definition of medicinal chemistry

History of medicinal chemistry

Importance of medicinal chemistry

Why we study medicinal chemistry?

Stages of medicinal chemistry

Stage one of medicinal chemistry

There are how many stages of medicinal chemistry

Stage two of medicinal chemistry

Stage three of medicinal chemistry

structure activity relationship

What is structure activity relationship?

What is SAR?

Design of medicinal chemistry

Importance of organic chemistry in medicinal chemistry

Importance of pharmacology in medicinal chemistry

Use of medicinal chemistry

Objectives of medicinal chemistry